Medications and your Health
Ask an Expert: Medications and Your Health
Click here to ask Daniel Kim a question about medications and your health
Latest Question
When should I take Synthroid®, first thing in the morning or just before I go to bed?
Daniel Kim's Response
It's generally recommended that levothyroxine (Synthroid®) be taken daily on an empty stomach, at least 30 minutes before food. The reason for this is that if you eat certain foods they may interact with levothyroxine, and less medication will make its way into the body. Your doctor may need to change your dose if absorption is impacted.
Some examples of foods that are known to bind to and prevent absorption of levothyroxine are:
- calcium and calcium-fortified orange juice
- cotton seed meal
- dietary fibre
- soybean flour (infant formula)
- walnuts
You should take this medication on an empty stomach to minimize any impact on absorption.
While most recommend taking the medication in the morning, you can also take it on an empty stomach at bedtime. A recent study confirmed that taking levothyroxine daily just before going to bed was an acceptable and effective alternative.
It is important that you are consistent in how you take your medication. You should take your medication in the same way and at approximately the same time each day.
Click here to ask Daniel Kim a question about medications and your health
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The information within this website is for Canadian audiences only. The information is for informational purposes only. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects. It should not be construed to indicate that the use of a particular drug is safe, appropriate or effective for you. It should not be relied upon or interpreted as a recommendation for any specific treatment plan, product or course of action. The information on the site is not intended as a substitute of any kind for professional medical advice, diagnosis or treatment. Speak to your healthcare professional before taking any product, changing your lifestyle, or beginning or discontinuing any course of treatment. If you suspect that you are ill or may have a medical emergency, contact a physician, a health professional or call 911 immediately.
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